There is, however, growing evidence that medications may speed recovery by enhancing some neurological functions without impacting others. The effective treatment of TBI requires input from multiple disciplines and professions starting at the time of injury and continuing through the rehabilitation phase.ĭespite the prevalence and cost of TBI-related disabilities there is a paucity of literature reviewing modern approaches to pharmacotherapy. A National Institute of Health panel estimates that 2.5 to 6.5 million Americans currently live with TBI-related disabilities. With advances in the management of head trauma, an increasing number of patients are surviving with residual neurological impairments. In the US, approximately 2 million people will sustain a TBI each year, one-quarter of whom will require hospitalization, leading to a conservative estimate of direct and indirect costs of $50 billion to $100 billion annually. CAMH also provides information related to the health and safety of persons living near the Brain Health Imaging Facility and to the environment.Traumatic brain injury (TBI) is commonly defined as an insult to the brain from an external force that causes temporary or permanent impairment in functional, psychosocial, or physical abilities.1 It is a significant cause of morbidity and mortality, and the leading cause of death and disability among young adults.Ĭommon causes of TBI include motor vehicle accidents, falls, sports injuries, and violence, and it is recognized increasingly in war zone injury. That information includes scientific and medical advances, funding announcements, and expansion of the program. As a result, members of the public are exposed to only negligible short-lived radiation levels that are far below natural radiation levels and regulatory limits.ĬAMH provides regular information to the public and specific stakeholders about the activities of its Brain Health Imaging Centre and their impact on the lives of individuals with mental illness or addictions. Small amounts of airborne short-lived radioactive gases may be released from time to time from a vent located on the top of the building about 50 meters above ground, so that the gases are widely dispersed and diluted before reaching ground level.
BRAIN MAPPING SOFTWARE USED TO TREAT CLOSED HEAD INJURIES FULL
To ensure full public safety, the CAMH cyclotrons are enclosed in thick concrete bunkers to shield the public from the radiation they produce when they are in operation.
Our discoveries are communicated to other scientists through scientific publications and conferences, and to the general public via the media and CAMH web site. For nearly three decades, CAMH has been a world leader in the application of cyclotrons and PET imaging to advance the understanding and improve the treatment of mental illnesses and addiction. The cyclotrons are particle accelerators that produce the short-lived positron emitting radionuclides for Positron Emission Tomography (PET), a technique that allows imaging of the brain chemistry.
CAMH Brain Health Imaging Centre cyclotronsĬAMH is licensed by the Canadian Nuclear Safety Commission (CNSC) to operate two cyclotrons at its College Street location. We are also pursuing the development of radiotracers to discover chemical brain markers that could identify the risk of illnesses such as Parkinson’s disease, Alzheimer’s disease and related dementias, traumatic brain injuries and their mental health consequences, autism spectrum disorder, suicide prevention, and addictions. Using these chemical brain imaging tools, our research has helped to more accurately calculate medication doses for depression and schizophrenia, identified targets for treatments of illnesses such as postpartum depression, and enabled academic centres and pharmaceutical companies to conduct more effective drug development. Our team at the Brain Health Imaging Centre have developed several imaging radiotracers used in PET brain research globally.
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